Cognomen לופסקו (Lupescu 
, לופסקו ) , worldwide, is quite a rare family name. The surname לופסקו is habitual in Romania, where it is quite a common surname, Israel, where it is a rare surname, and Denmark. Measured by absolute frequency, this name is the most popular in Romania, the United States, and Israel. Very seldom, לופסקו is the forename as well as the last name.
| VARIANT | COUNTRY |
|---|---|
| Lupescu | Romania, France, Italy, United States, Israel |
| לופסקו | Israel |