Surname Opoku (Opoku 
, Нана 
) , worldwide, is a common cognomen. The last name Opoku is habitual in Ghana, where it is a common surname, Bulgaria, where it is quite a rare surname, and Qatar. In absolute terms, it is commonest in Ghana, the United States, and the United Kingdom. Very seldom, Opoku is the forename as well as the last name.
| opoku ware i King of the Ashanti people, GH (b. 1700) |
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| opoku fofie (b. 1800) |
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| theophilus opoku Gold Coast linguist, educator and missionary, GH (b. 1842) |
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opoku ware ii King of the Ashanti people of Ghana (1919-1999), GH (b. 1919) |
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isaac yaw opoku Ghanaian politician, GH (b. 1957) |
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| albert opoku Ghanaian choreographer, dancer, artist, and educator, GH (b. 1915) |
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| albert mawere opoku Ghanaian choreographer, dancer, artist, and educator, GH (b. 1915) |
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hilde opoku Norwegian politician, NO (b. 1968) |
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eric opoku Ghanaian politician, GH (b. 1970) |
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anna gifty opoku-agyeman Ghanaian-born American activist, writer, CEO, GH |
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kwame antwi-agyei opoku social entrepreneur, public speaker, GH |
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| solomon kwame opoku Politician (b. 1931) |
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eric opoku Ghanaian footballer, GH (b. 1991) |
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| opoku preko Ghanaian politician (b. 1943) |
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| opoku afriyie Ghanaian footballer (1945-2020), GH (b. 1945) |
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