Last name Sissoko (Sissoko 
, シソコ, سيسوكو) , globally, is a common cognomen. The family name Sissoko is characteristic of Sub-Saharan Africa, particularly Mali, where it is a common surname, Gambia, where it is quite a common surname, and Gabon (explore the name in all countries). Measured by absolute frequency, it most frequently occurs in Mali, France, and Ivory Coast. Very seldom, Sissoko is the forename as well as the last name.
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| Sissoko | Mali, France, Senegal, Ivory Coast, Algeria |
| bazoumana sissoko Malian jeli and n'goni player (1890–1987), ML (b. 1890) |
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| fily dabo sissoko Malian politician, ML (b. 1900) |
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baba sissoko Malian musician, ML (b. 1963) |
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| inna sissoko Malian politician, ML (b. 1933) |
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mohamed sissoko association football player, FR (b. 1985) |
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moussa sissoko French association football player, FR (b. 1989) |
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abdoulwhaid sissoko footballer, FR (b. 1990) |
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ibrahim sissoko Ivorian footballer, CI (b. 1991) |
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| charles samba sissoko (b. 1932) |
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| mariam sissoko First Lady of Mali, ML (b. 1944) |
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ibrahim sissoko French association football player, FR (b. 1995) |
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| cheick oumar sissoko Malian film director and politician, ML (b. 1945) |
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| molobaly sissoko Malian football manager, ML (b. 1945) |
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alpha sissoko French association football player, FR (b. 1997) |
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kadiatou sissoko French basketball player (1999-), FR (b. 1999) |
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