Family name Isayeu (Isayeu 
) , across the world, is a very rare cognomen. The last name Isayeu is habitual in Latvia, where it is a rare surname, Belarus, and Chile, where it is an extremely rare surname. Measured by absolute frequency, it is commonest in Belarus, Latvia, and Germany.
| VARIANT | COUNTRY |
|---|---|
| Isayeu | Germany, Belarus, Chile, United States, Latvia |