Family name Palacio (Palacio 
, بالاسيو 
, Паласио 
) , throughout the world, is a widespread cognomen. The surname Palacio is habitual in Latin America and the Caribbean, particularly Belize, where it is a common surname, Panama, and Colombia (explore the name in all countries). In absolute terms, it is the most numerous in Colombia, Argentina, and Philippines. Much less frequently, Palacio is the forename as well as the last name.
| diego garcía de palacio Spanish sailor and scientist (1540-1595), ES (b. 1540) |
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| santiago de laysequilla y palacio Spanish politician, ES (b. 1630) |
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| antonio de palacio y palacio (born 1724) (b. 1724) |
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mariano riva palacio former Mexican Secretary of Finance, Justice, congressman and thrice Governor of the State of Mexico (1803-1880), MX (b. 1803) |
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romualdo palacio y gonzález Spanish general and governor of Puerto Rico (1827-1907), ES (b. 1827) |
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manuel del palacio Spanish poet (1831-1906), ES (b. 1831) |
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vicente riva palacio Mexican politician, MX (b. 1832) |
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| santiago de palacio Argentinian politician and merchant, AR (b. 1784) |
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francisco javier de palacio y garcía de velasco Spanish politician, ES (b. 1840) |
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eduardo de palacio ES (b. 1835) |
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raimundo andueza palacio President of Venezuela (1846-1900), VE (b. 1846) |
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armando palacio valdés Spanish author (1853-1938), ES (b. 1853) |
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| ramón palacio ES (b. 1793) |
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dámaso e. palacio Argentinian judge and politician (1855-1923), AR (b. 1855) |
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alberto de palacio Spanish architect and bridge engineer, ES (b. 1856) |
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