Last name Radcliffe (Radcliffe 
, ラドクリフ 
, רדקליף 
) , around the globe, is a common cognomen. The last name Radcliffe is habitual in Isle of Man, where it is quite a common surname, Jamaica, where it is quite a rare surname, and the United Kingdom. Measured by absolute frequency, it is the most numerous in the United States, the United Kingdom, and Australia. Very seldom, Radcliffe is the forename as well as the last name.
| john radcliffe English knight and administrator, died 1441 (b. 1350) |
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| thomas radcliffe (b. 1391) |
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robert radcliffe, 1st earl of sussex English Earl, GB (b. 1483) |
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| thomasine radcliffe 1448- (b. 1447) |
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| jeremiah radcliffe British scholar (b. 1501) |
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| margaret radcliffe (1510-1583) (b. 1510) |
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| ralph radcliffe English schoolmaster and playwright (b. 1519) |
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| henry radcliffe British Earl (b. 1530) |
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| john radcliffe English politician (b. 1539) |
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| mary radcliffe Radcliffe, Mary (c.1550–1617/18), courtier (b. 1550) |
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| margaret radcliffe English abbess, FR (b. 1582) |
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| george radcliffe English politician, NL (b. 1593) |
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john radcliffe English physician, academic and politician (1650-1714), GB (b. 1650) |
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| alexander radcliffe English politician (b. 1608) |
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| ann radcliffe (born 1626) (b. 1626) |
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