Cognomen Serapio (Serapio 
, Серапион 
, Серапіон 
) , all over the world, is a common last name. The family name Serapio is characteristic of Latin America and the Caribbean, particularly Nicaragua, where it is quite a common surname, Mexico, where it is quite a rare surname, and Honduras. In absolute terms, the name is most common in Mexico, Philippines, and Argentina. Likewise, Serapio is the forename as well as the last name.
| marcus rapilius serapio IT (b. 100) |
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| publius cornelius scipio nasica serapio Roman consul 138 BC, TR (b. 180) |
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| víctor trabazo serapio ES (b. 1896) |
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| antonio serapio Filipino politician, PH (b. 1937) |
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| carlos serapio Philippine lawyer and political consultant, PH (b. 1950) |
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| ignacio serapio |
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| virgilio trabazo serapio ES |
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| kevin serapio Nicaraguan footballer, NI (b. 1996) |
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