Family name Serio (Serio 
, Sarius 
, سيريو 
) , worldwide, is a common last name. The last name Serio is characteristic of Italy, where it is quite a common surname, Portugal, where it is quite a rare surname, and Argentina. Measured by absolute frequency, it is commonest in Italy, the United States, and Brazil. Very seldom, Serio is the forename as well as the last name.
| rosa maria serio (b. 1674) |
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| luigi serio IT (b. 1744) |
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francesca serio Italian politician, IT (b. 1903) |
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| angelo serio Italian jockey, IT (b. 1889) |
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michele serio Italian writer, IT (b. 1954) |
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serio digitalino Italian painter and sculptor, IT (b. 1956) |
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manlio serio Italian lawyer and politician, IT |
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| john a. serio (b. 1921) |
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| salvatore serio Italian astronomer, IT (b. 1941) |
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| serio de guidi (b. 1931) |
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michele de serio volleyball player, IT (b. 1996) |
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| renato serio Italian composer and conductor, IT (b. 1946) |
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| mario serio (b. 1937) |
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| john n. serio (b. 1943) |
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| francisco corrêa serio person identified in the Museu da Pessoa collection, BR (b. 1953) |
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